Mathis MW, Mathis A, Uchida N. Somatosensory Cortex Plays an Essential Role in Forelimb Motor Adaptation in MiceNeuron. 2017. 10.1016/j.neuron.2017.02.049. 

•Mice exhibit motor adaptations to forelimb force field-based perturbations

•Optogenetic inhibition of forelimb somatosensory cortex (S1) abolished motor adaptation

•The same photoinhibition did not impair motor control or reward-based learning

•S1 plays an essential role in updating the memory about forelimb motor perturbations

News piece at the Dept. website


 Mathis et al, 2017. Neuron

Mathis et al, 2017. Neuron


Li H, Kuwajima T, Oakley D, et al. Protein Prenylation Constitutes an Endogenous Brake on Axonal GrowthCell Reports. 2016.16 (2) :545 - 558. 


Ho R, Sances S, Gowing G, Amoroso, MW, et al. ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks. Nature Neuroscience, 2016.


Cohen JY, Amoroso MW, Uchida N. Serotonergic neurons signal reward and punishment on multiple timescaleseLife. 2015. 10.7554/eLife.06346
Read the eLife Insight here (By Peter Dayan and Quentin Huys) 
Recommended by F1000


Re D B, Le Verche V, Yu C, Amoroso, MW,  et al. Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALSNeuron. 2014. 81 :1001 - 1008. 
Read the Neuron review here (By Sheila K. PiroozniaValina L. DawsonTed M. Dawson)



Amoroso MW, Croft GF, Williams DJ, et al. Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells. Journal of Neuroscience. 2013. 33 (2) :574 - 586.
Read the Journal of Neuroscience Journal Club article here 

               Kanning KC, Li H, Nikulina E, et al. Making motor axons grow. 2012. 30 (8) :613 - 614.


Nédelec S, Peljto M, Shi P, et al. Concentration-Dependent Requirement for Local Protein Synthesis in Motor Neuron Subtype-Specific Response to Axon Guidance Cues. Journal of Neuroscience, 2012. 32 (4) :1496 - 1506. 


Takazawa T, Croft GF, Amoroso MW, et al. Maturation of Spinal Motor Neurons Derived from Human Embryonic Stem Cells. PLOS ONE, 2012. 7 (7) :e40154. 



Boulting GL*, Kiskinis E*, Croft GF*, Amoroso, MW*, Oakley, D* et al. A functionally characterized test set of human induced pluripotent stem cells. Nature Biotechnology, 2011. 29 (3) :279 - 286. 
*co-first authors


Bock C, Kiskinis E, Verstappen G, et al. Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell, 2011.144 (3) :439 - 452. 

(please note M.W. Mathis was M.W. Amoroso)

For unpublished work, please see our pre-print & abstracts page